Industry-leading
hollow microneedles

Industry-leading hollow microneedles

Our silicon microneedles deliver unmatched precision and sharpness, combined with the strength, durability, and biocompatibility that only MEMS manufacturing can provide at this scale.


Integrated capillary system

The needles on each chip are connected using an integrated capillary system that drives the fluid towards a collection reservoir or a sensing element.

The capillaries are designed and manufactured for optimal fluidic properties using a combination of deep reactive ion etching of silicon and anodic glass bonding.

System engineering

Microneedles are central to our solution, but they don’t work alone. Clinically reliable dISF sampling requires a fully integrated system. 

Our PELSA system combines precision pressure control to ensure consistent penetration with minimal skin trauma, an integrated microfluidic network to collect and transport dISF, and real-time imaging for continuous quality assurance.

This is complemented by automated sampling protocols developed with our partners to reflect real-world workflows, and a strong focus on safety and biocompatibility through sterile, single-use microneedles.

System engineering

Microneedles are central to our solution, but they don’t work alone. Clinically reliable dISF sampling requires a fully integrated system. 

Our PELSA system combines precision pressure control to ensure consistent penetration with minimal skin trauma, an integrated microfluidic network to collect and transport dISF, and real-time imaging for continuous quality assurance.

This is complemented by automated sampling protocols developed with our partners to reflect real-world workflows, and a strong focus on safety and biocompatibility through sterile, single-use microneedles.

Integrated capillary system

The needles on each chip are connected using an integrated capillary system that drives the fluid towards a collection reservoir or a sensing element.

The capillaries are designed and manufactured for optimal fluidic properties using a combination of deep reactive ion etching of silicon and anodic glass bonding.

Innovation Portfolio

Ascilion currently holds 75+ patents across 12 patent families

Innovation Portfolio

Ascilion currently holds 75+ patents across 12 patent families.

Ascilion has been recognized as being in the top 1% of the 12,000 innovations funded by the EU for our minimally invasive system for dermal interstitial fluid sampling and collection. Furthermore, we have been recognized as a Key Innovator by the EU Innovation Radar for the project “Novel biomarker wearable for interstitial fluid extraction and analysis”.

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